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Advanced Featuring UC-II® Collagen - 30 Capsules (30 Servings)
(278 Reviews)
$64.99
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Recent Reviews

The Real Deal

Very good product . It really works.

Verified Buyer

Great product

Have been taking it for about 45 days and I see a noticeable difference in my legs. It has increased my mobility and endurance.

Verified Buyer

Hopeful!!

Instaflex was a better price at GNC then online. I have extremely bad arthritis and was hoping this would help make it less painful. It helps very little compared to when I don't take it, At this point I've been using it for about a month.

Verified Buyer

Sorry but I haven't received my order of January 12th. Think this is a scam. Very disgusting.

Verified Buyer

Doesn't work for me. Some relief initially but over time, not effective.

Verified Buyer

daily routine before the gym

I count on this with 70+ year old knees.

Verified Buyer

Good price and promptly sent. Good job!

Verified Buyer

Best thing

Best thing I could take for my knee? felt the results in a few days?

Verified Buyer

Hasn't arrived

Ordered it, paid for it but hasn't arrived after 30 days.

Verified Buyer

Good product

The pills along with the cream works well together.

Verified Buyer

Like a magic wand !!!!

I just started this a couple of weeks ago and already have recommended it to all my friends , I went from not being able to walk because of the severe pain in my knee and not being able to lift my shoulder to walking and using my shoulder, I am going to have hylurounic acid injections and acupuncture in order to avoid knee replacement surgery , but this product does work , thank you Marie Osmond for your input , don't doubt it , try it, I felt the difference the next day.

Verified Buyer

Change is good

Needed to drop Glucosamine Condroitin due to sodium content. Love the change (and only one per day instead of two with GC)

Verified Buyer

Satisfied customer

I have used glucosamine & condriitan many years but it was no longer giving me relief. Since I changed to instaflex advanced I am having much less pain and discomfort. I recommend it and suggest you try it for 2 weeks to see for yourself. GNC also has the best price .I do wish it came in a smaller pill rather than a cspsule!

Verified Buyer

it has helped my knees

Verified Buyer

RELIEF

This product speaks for itself!! It is GREAT!!!Try it if you haven't yet. You will not regret it !!!!!! I am thankful I tried it. I feel sooooo much better now. Been taking it for a month and two weeks. Will be reordering!!!!!

Verified Buyer

Thanks GNC

Thank you, please keep prices low for seniors, God bless + America

Verified Buyer

Pain free and healing

I went from three pills that took the edge off to just this one. After almost 3 months I now wake up pain free! I'm younger - mid 40ies - but I had a hard fall on my knee and it wasn't healing. I saw an orthopedic specialist who recommended PT but I really needed to strengthen my muscles and heal the injury and glucosamine wasn't helping. THIS on the other hand immediately took the pain away and let me get back to physical activities to get stronger again. If you need a knee or hip replacement

Verified Buyer

So far, so good!

I have PFS in both knees. I suffered greatly during cold eastern Oregon winter. I started taking this 4/1/25. Since, my knee pain is greatly reduced, the stiffness is down to about 20%, and I'm able to walk 2 miles a day again. Why not 5 stars? Well, I need to try for a full year to see if its the warmer weather that's causing great improvement or this pill. I've always been a skeptic about internet drugs. Wait for my next update in 7 or 8 months.

Verified Buyer

Yes I been taking it but in two months I stopped it . But I am taking it agin. It is good vitamin for knee pain . It is really helpful to knee pain . Thank you ?? ??

Verified Buyer

It really worked

I did not expect it to work my very first time I took it I didn't have any pain or take it from my hip on my knees and religiously taking it every day since some days I'm very good another days I still hurt this is the truth I have to go to an orthopedic surgeon with the medicine I'm very pleased with..

Verified Buyer

This product really works!

I get Synvisc shots in both knees. It didn't work in my left knee. The pain was there almost daily. Thought I would try Instaflex Advance. After 2 weeks, no more pain. I am a believer and will continue to use daily. Glad I tried this product instead of getting a knee operation

Verified Buyer

I'm getting nothing from taking these.

Verified Buyer

I was taking it from another company ..so I really like this thing. I just started my bottle from you but will be reordering it when I am close to needing it again. my pain is now bearable excepting when first getting up in the morning.... thanx . will re order soon.....

Verified Buyer

Allows me to resume life!

Very satisfied. Allows me to keep going and my knee to bounce back after over use very quickly. So very happy with this product!!

Verified Buyer

My knees are thankful

It works great. I encourage anyone to try it.

Verified Buyer

this product is helping me not feel the affects of my early onset arthritis. I'm 55 years old. I will continueto use this. Probably until I'm dead. Dennes Mathews

Verified Buyer

Highly recommend Instaflex Advanced, it has reduced the stiffness in my knees.

Verified Buyer

Come early and the product is excellent

Verified Buyer

Cut pain by 75%!

I have tried many item for my knee pain since 1998. Instaflex is the first one that worked after about a week. Cutting the pain by about 75%. Great product!

Verified Buyer

I appreciate the fact that the several supplements needed in my situation are in one daily pill.

I went from crippling pain to comfortable joint functioning seven years ago and never looked back.

Verified Buyer

Knees markedly better

I do not know if it is these pills or what, but my Knees, now bone on bone, are far less painful than they were. I am crediting these pills to it.

Verified Buyer

Better Knee joint

I am very happy with this product. 55 years ago I sustained battle damage to my left knee. For the last several years I have suffered with joint discomfort and soreness and nothing I have taken has eased that. Since I started taking this product about 20 days ago my knee is doing much better. The soreness has gone.

Verified Buyer

Miracle pill

Great product, started feeling the results after just a few days, highly recommend

Verified Buyer

Miracle in a Bottle

Love this product. Helps me walk with ease. Husband loves it also.

Verified Buyer

THANK GOODNESS FOR THIS PRODUCT

Before ordering this I didn't really think it would work. Let me tell you it does for me. I am 68 years old and been on it for 2 years and it stopped my knees from hurting every single day. I still have back issues, but having the pain gone from my knees is a blessing for sure.

Verified Buyer

Instaflex - Where have you been all my life?

I started using Instaflex Advanced a few months ago and it has changed my life. I suffer from joint pain along with arthritis throughout my body. This product has allowed me to move more easily and without groaning at every step. I've used Oseo Bi-Flex for years but it's now bye bye O B and hello Instaflex. It is well worth the price. Don't hesitate. Buy it. You won't regret it.

Verified Buyer

I highly recommend this product. It works great. Definitely see a difference in my joint flexibility!??????????

Verified Buyer

Great product

Within a week I started to feel less knee pain. Now a month into taking it I am almost pain free.

Verified Buyer

It must be doing something right

I bought this for my mom who has MS and arthritis years ago and she still avidly takes it. She is never receptive to things buy her.

Verified Buyer

Truly a good product!

I really believe it has helped me so much.

Verified Buyer

Really Helps!

Working long hours from home means hours of sitting behind the computer. This really helps loosen up the aging joints. Now a permanent part of the morning meds.

Verified Buyer

It really helps with aching joints

Verified Buyer

I have definitely felt a difference in my joints when standing and walking long periods of time.

Verified Buyer

So far so good (16 days)

So far so good. Until now I have been taking it for 16 days. I will give my opinion again later on.

Verified Buyer

Instaflex and my joints

I have taken Instaflex for 3 months and I have better joint movement and less pain in my knees and shoulders

Verified Buyer

Instaflex advanced

I find that I have less knee pain since I've been taking this, but I have also been getting knee injections so it's hard to tell If the pills are making that much of a difference. That being said, I do buy it when it goes on sale or I have a coupon. Truth be told you can find it cheaper elsewhere than at GNC.

Verified Buyer

Good for arthritis

My husband takes this for arthritis in his knees, he says it works better than anything else he has tried for the knee pain.

Verified Buyer

Works as the commercial says.

I am pleased with Instaflex I am not in pain anymore, I can bend down and move a lot better.

Verified Buyer

My husband noticed a significant improvement in his joint pain after 2 weeks

Verified Buyer

insaflex

helps me walk better with no paip.

Verified Buyer

This works!

After a couple of weeks I noticed a reduction in that dull pain I've had in my arthritis points (feet and ankles). I will keep using this - amazing!

Verified Buyer

Instaflex.

The serves is professional.

Verified Buyer

Price is a bit high

It works well with the pain in my knees. But the price for a 30 capsule bottle is on the steep side.

Verified Buyer

It's a little expensive for my husband and I but it works.

Verified Buyer

They are taking longer then I thought but it seems somewhat they are working

Verified Buyer

Moderate improvement.

Verified Buyer

Advanced Featuring UC-II® Collagen

I can actually feel the difference almost within the 1st day of taking the Advanced Featuring UC-II® Collagen

Verified Buyer

Instaflex

Good so far

Verified Buyer

Miracle for fibromyalgia

I'm always looking for miracles to help with fibromyalgia pain but realistically nothing ever really lasts. Instaflex has been the exception. I tried it for 30 days and noticed a difference then stopped it because I ran out and wasn't really convinced. Within 3 days of being off of the supplement I could feel every ache and pain return. I assumed I just overdid some activities but after 2 weeks I went to GNC to buy more and again after a few days I knew the product was really working small miracles as promised. I absolutely will continue to use instaflex as long as the results continue.

Verified Buyer

It Really Works!

Hip and knee pain started improving day 1! By day 3, I was back walking in my fast stride comfortably and by day 7, I was bending and moving painlessly. This product delivered as promised!

Verified Buyer

Not bad

It actually works rather well for me. Joint pain has reduced

Verified Buyer

Recommended

Great, felt relief immediately

Verified Buyer

I have only used it for 1 week and my shoulders feel much better

Verified Buyer

Instaflex

using for many years—helps my knee which i hurt over 30 years ago—no pain for many years since i started using it

Verified Buyer

Still Hurting

Nothing nice to say at the moent.

Verified Buyer

Great product

Love this product

Verified Buyer

I like the ease of finding my product right away and the friendly, courteous attitude of the sales clerk.

Verified Buyer

Product is not as effective as they say it is but I use it because it helps somewhat.

Verified Buyer

Great.

This stuff really works. I would live without it.

Verified Buyer

It’s helps with my knee problems

Verified Buyer

The product did what it said it would do, it helped my joints not to ache,BUT had to stop taking because irritated ?? my stomach. SORRY.

Verified Buyer

intaflex

It did not help me to feel any better

Verified Buyer

Initially seemed like it was working

Initially seemed like it was working, but recently I've seen no significant improvement in my knee pain

Verified Buyer

Hasn't help, knee hurts more since starting Instalex. Will continue for a short time.

Verified Buyer

I feel like the 15 day trial are stronger than the new bottle I ordered.

Verified Buyer

It seems to me there is major price-gouging going on here. It's on the backs of desperate, low income retirees. Shame!!

Instaflex Adv. is like a miracle! It worked in 2 days to greatly relieve back, knee, shoulder pain. I just wrote a bad check at Amazon, for $103 for 30. I'm officially a drug addict now. God help me.

Verified Buyer

Good. I'll keep taking it

It seems to be helping a bit. It still hurts but I am moving a little bit better

Verified Buyer

Tobis

It worked for my joints, But it tore up my stomach. Had to stop taking it! Stoped the scriptions.

Verified Buyer

It is a great product

It works well, it does what it is supposed to do.

Verified Buyer

Can't tell a difference.

Neither Good, Nor Bad. Simply cannot tell a difference in any way. So at least it's not toxic.

Verified Buyer

I like the way it works

Verified Buyer

I was skeptical but definitely feel better

Verified Buyer

Great product!

I have been using this product for over a year. Originally, I bought it after seeing a TV ad. I have taken many similar products over the years (arthritic knees -- not much cartilage left!) I noticed a difference within 2 weeks from what I had been taking. It is expensive, but for me, it is worth it. I still can't run/jog like I could 10 years ago but most days I'm relatively pain free.

Verified Buyer

Great product

My husband swears by this product for his bad knee.

Verified Buyer

Instaflex got me moving!

After transitioning into a new role at work that requires me to walk and stand for 8 and sometimes 11 hours a day, my knee joints hurt so badly I could barely get to my car at the end of the day. I knew I needed something to alleviate the pain and getting me moving. Instaflex really does the job for me and I don’t know where I would be without it!

Verified Buyer

So far 2 my legs/knees feels somewhat better let you know after 2nd bottle. or as soon as I see real improvement

Verified Buyer

Eased the Pain

I bought this a month ago, and it has worked really well to ease the pain I feel daily in my joints, specifically in my hands. I'm a long time supplement user, and I'm glad I've finally found something that actually helps me feel better!

Verified Buyer

Complete joint freedom!

Was taking glucosamine chondroitin + MSM for years until it stopped working. My 85 yr. old mom told me about InstaFlex Advanced so I tried it. After 7 days I have complete joint freedom. My hands, shoulders, knees, all pain free. And no medications!!!

Verified Buyer

so far so good - not there yet but getting there it has only been a couple of weeks

Verified Buyer

Worked far better than OmegaXL, which turned out to be a waste of my money for months.

There were no dislikes. I was happy with the results I am seeing. Up until6-9 weeks ago, I was unable to get on my knees easily, and raising up was torture but not anymore. the pain is nearly all gone. I am so happy.

Verified Buyer

Relieved my pain and striffness, Taking 3 yrs now

Verified Buyer

Instaflex

On my second bottle. Not really feeling any different. I will be testing out a different brand from a different store on my next purchase.

Verified Buyer

Instaflex

Be fore very good , this time for prepared if happen be cause my job heavy for me

Verified Buyer

I almost stopped taking them after 2 months but am so glad I did not. I highly recommend this product.

After taking Instaflex capsuls for 3 months, my arthritic knee was 95% better. The pain when walking or getting up from sitting for a while is almost completely gone.

Verified Buyer

Helps my knees

Seems to be helping with my sore knees.

Verified Buyer

Can’t live without it.

It really helps knee soreness.

Verified Buyer

Citizen

Too expensive, plus I did not notice any difference.

Verified Buyer

Instaflex helps with the arthritis in my hands

Verified Buyer

Instaflex

I bought this product and plan to continue using it

Verified Buyer

I love instaflex, however it is a little pricey.

Instaflex is the only supplement for knee pain that has worked for me. I love it!

Verified Buyer

I did not like this as well as the regular Instaflex. I do not think it helped my joints as well. I went back to the regular after trying this for 2 weeks.

Verified Buyer

Good product

I use this regularly, its proven beneficial

Verified Buyer

Have been using it long enough to tell a difference

Verified Buyer

Game changer

After taking for 2 weeks, I started to notice an improvement. My son in law recommended taking Tart Cherry with it. That was definately a game change. Now 4 weeks later I am virtually pain free and can walk without crying or cringing in pain. Thank you for an amazing product.

Verified Buyer

May have to take it for longer period

Did not notice any significant improvement after three weeks, probably is too soon to tell

Verified Buyer

Relieve Joint Pain

I have used Instaflex successfully for several years. Love it!

Verified Buyer

good

Product very good

Verified Buyer

I am ready for a refill

Verified Buyer

I would definitely recommend this to anyone to help with inflammation

Instaflex has brought me a great deal of relief to my knees & hands. It reduced the swelling in about a week and I’m feeling much better.

Verified Buyer

Works as advertised for me give me added confidence

Verified Buyer